A
key to the abbreviations used and information
on the different
anti-malarial drug regimens can be found
below the main tables
COUNTRY
MAL
1
MAL
2
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Afghanistan malaria
risk below 2000 metres from May to Nov
2
-
C
R
R
R
R
-
-
L
L
L
Armenia malaria
risk from June to Oct
3
-
-
R
R
R
R
-
-
L
L
L
Azerbaijan malaria
risk in the south border area and Khachmas
from June to Oct
3
-
-
R
R
R
R
-
-
L
L
L
Bahrain No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Bangladesh malaria
risk in the south east and Chittagong
Hill Tracks, regimen 1, all other areas
regimen 2, no risk in Dhaka city, regimen
4
1/2
2
C
R
R
R
R
-
R
L
L
L
Bhutan No
malaria risk
2
-
C
R
R
R
R
R
-
L
L
L
Brunei No
malaria risk
-
-
C
R
R
R
R
-
R
L
L
L
Cambodia malaria
risk in all areas regimen 1 or 2, western
provinces & border with Thailand,
regimen 1 but mefloquine resistance
present, no risk in Phnom Penh, regimen
4
1
2
C
R
R
R
R
-
R
L
L
L
China malaria
risk in Yunnan Province and Hainan Island,
regimen 1 or 2, all other rural areas,
regimen 3, main tourist areas - very
little risk, avoid mosquito bites, regimen
4
1/3
4
2
C
R
R
R
R
-
R
L
L
L
Georgia malaria
risk in south eastern areas from July
to Oct
3
-
-
R
R
R
R
-
-
R
L
L
Hong
Kong Very
low malaria risk avoid mosquito bites
4
-
-
R
R
R
R
-
R
L
L
L
India malaria
risk in the whole country including
Goa regimen 2 or 1, no risk in northern
mountain states, regimen 4
2
1
C
R
R
R
R
R
R
L
L
L
Indonesia
including Bali malaria
risk in Irian Jaya, East Timor and Lombok
- regimen 1. All other areas except
cities - regimen 2, Low risk in main
cities & Bali - regimen 4
2/1
4
1/2
C
R
R
R
R
-
R
L
L
L
Iran malaria
risk from March to Nov
2
-
-
R
R
R
R
-
-
L
L
L
Iraq malaria
risk in the rural north and Basrah province
from May to Nov
2
3
C
R
R
R
R
-
-
L
L
L
Israel No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
COUNTRY
MAL
1
MAL
2
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Japan No
malaria risk
-
-
-
-
-
R
R
-
R
L
L
L
Jordan No
malaria risk
-
-
C
R
R
R
R
-
-
L
L
L
Kazakhstan No
malaria risk
-
-
C
R
R
R
R
-
-
L
L
L
Korea
(North) No
malaria risk
-
-
-
R
R
R
R
-
R
L
L
L
Korea
(South) No
malaria risk
-
-
-
R
R
R
R
-
R
L
L
L
Kuwait No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Kyrgystan No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Laos malaria
risk in the whole country (regimen 1),
except Vientiane (regimen 4)
1
2
C
R
R
R
R
-
-
L
L
L
Lebanon No
malaria risk
-
-
C
R
R
R
R
-
-
L
L
L
Malaysia malaria
risk in deep forests of peninsular Malaysia,
Borneo including Sarawak and Sabah,
regimen 1 or 2, all other areas including
Kuala Lumpur & Penang, regimen 4
1/4
2
C
R
R
R
R
-
R
L
L
L
Maldives No
malaria risk
-
-
C
R
R
R
R
-
-
L
L
L
Mongolia No
malaria risk
-
-
-
R
R
R
R
R
-
L
L
L
Myanmar
(Burma) malaria
risk on Thai border areas
1
2
C
R
R
R
R
-
-
L
L
L
Nepal malaria
risk in areas below 1200 metres, regimen
2, all other areas, regimen 4
2/4
-
C
R
R
R
R
R
R
L
L
L
Oman malaria
risk in rural areas
2
-
C
R
R
R
R
-
-
L
L
L
Pakistan malaria
risk in areas below 2000 metres
2
1
C
R
R
R
R
-
R
L
L
L
COUNTRY
MAL
1
MAL
2
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Philippines malaria
risk in rural areas below 600 metres,
regimen 2 or 1, no risk in Manilla,
Cebu, Leyte, Bohol & Cantanduanes
2
1
C
R
R
R
R
-
R
L
L
L
Qatar No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Russia No
malaria risk
-
-
-
R
R
R
R
-
-
R
L
L
Saudi
Arabia malaria
risk in all areas (regimen 2) except
Northern, Eastern and Central provinces
& the Asir Plateau. Western border
cities, very little risk (regimen
4)
*meningococcal
vaccination is now mandatory for pilgrims
on Hajj to Mecca, otherwise recommended
for stays of one month or more
2/4
-
C
R
R
R
R
M*
R*
-
L
L
L
Singapore No
malaria risk
-
-
C
R
R
R
R
-
-
L
-
L
Sri
Lanka malaria
risk in the whole country except Colombo,
Kalutara & Nuwara Eliya
2
-
C
R
R
R
R
-
R
L
L
L
Syria malaria
risk in northern borders from May to
Oct
3
-
C
R
R
R
R
-
-
L
L
L
Taiwan No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Tajikistan malaria
risk from June to Oct
3
-
-
R
R
R
R
-
-
L
L
L
Thailand malaria
risk in border areas with Cambodia,
Laos & Myanmar and Koh Chang Island
- regimen 1 but mefloquine resistance
present. All other areas including Bangkok,
Pattaya, Phuket, Chiang Mai & River
Kwai Bridge, regimen 4
1/4
-
C
R
R
R
R
-
R
L
L
L
Turkey malaria
risk in Antalya, Side, Alanya, the east
coast, south east Anatolia and the plain
around Adona from May to October. No
risk west of Antalya
3
-
-
R
R
R
R
-
-
L
L
L
Turkmenistan malaria
risk from June to Oct
3
-
-
R
R
R
R
-
-
L
L
L
United
Arab Emirates malaria
risk in the northern rural areas
2
-
-
R
R
R
R
-
-
L
L
L
Uzbekistan No
malaria risk
-
-
-
R
R
R
R
-
-
L
L
L
Vietnam malaria
risk in the whole country except major
cities, the Red River delta area and
the coastal plain north of Nha Trang
1
-
C
R
R
R
R
-
R
L
L
L
Yemen Malaria
risk in the whole country all year round
except Aden and the airport perimeter
where the risk is minimal.
2
1
-
R
R
R
R
-
-
L
L
L
YEL
Yellow
Fever
HEP
A
Hepatitis
A
TYP
Typhoid
TET
Tetanus
POL
Polio
MEN
Meningitis
ENC
Encephalitis
B
DIP
Diphtheria
RAB
Rabies
HEP
B
Hepatitis
B
M
Vaccination
is mandatory and a certificate
of vaccination is required for
entry.
C
A
certificate of vaccination may
be required if entering from an
endemic country, (except for children
<1 year old).
R
Vaccination
is recommended for the country
but no evidence is required
for entry.
L
Long
Term. Vaccination recommended
for travellers staying in endemic
areas for 3 months or more.
Countries
requiring malaria prophyllaxis
should be regarded as being at risk
all year round and you should
also assume that the whole country
is at risk unless otherwise indicated.
The 1st malaria regimen (MAL
1) is the preferred regimen
for a country. The 2nd malaria
regimen (MAL 2) is an alternative
that should only be used when the
1st Regimen is either unavailable
or badly tolerated. The preferred
regimen should always be used whenever
possible. Use of the 2nd regimen in
some instances may not provide adequate
cover.
When
there are two different regimens
for the same country, they are area
specific. Read the text to find out
which regimen is suitable for the
area you require.
Where regimen 1 is indicated
there is Chloroquine resistance in
that region and it is very likely
to be the Falciparum malaria which
is the most serious form of the disease.
In this instance it is vitally important
that travellers take adequate prophylaxis.
Remember:- No prophylaxis is
100% effective but not taking anti-malarials
where they are indicated will put
you at greater risk should you get
the disease. Malaria is a killer!
The
Different Drug Regimens
Regimen
1
Mefloquine
one 250mg tabletweekly.
OR
Doxycycline one 100mg capsule daily.
OR
Malarone one tablet daily.
No
prophylactic tablets required but
anti mosquito measures such as insect
repellents, mosquito nets, long sleeved
clothing, etc. should be strictly observed.
.
Proguanil
100mg
tablets are supplied as Paludrine
Tablets
Chloroquine
150mg
tablets are supplied as Nivaquine
or Avloclor Tablets
Mefloquine
250mg
tablets are supplied as Lariam
Tablets
Malarone
is
a combination of Atovaquone 250mg
and Proguanil 100mg
Length
of Prophylaxis
Chloroquine,
Proguanil & Maloprim
Start
one week before travel, throughout
your stay in an endemic area and continue
for four weeks after return.
Mefloquine
(Lariam)
Start
two and a half weeks before travel,
throughout your stay in an endemic area
and continue for four weeks after
return.
Doxycycline
Start
two days before travel, throughout
your stay in an endemic area and continue
for four weeks after return.
Malarone
Start
two days before travel, throughout
your stay in an endemic area and continue
for one week after return.
IMPORTANT!
Take
the tablets absolutely regularly,
preferably with or after a meal.
Long
Term Use of Anti-Malaria Drugs
Chloroquine
May
be taken for periods exceeding five
years.
Paludrine
May
be taken for periods exceeding five
years.
Maloprim
Can
be taken for periods up to one year.
Mefloquine
Can
be taken for periods up to one year.
Doxycycline
Can
be taken for periods up to six months.
Malarone
Can
be used for travel periods up to three
months.
Compatibility
of Anti-Malaria Drugs
Pregnancy
Breast
Feeding
Epilepsy
Psoriasis
Altitude
Scuba
Diving
Chloroquine
OK
OK
NO
NO
OK
OK
Paludrine
OK
OK
OK
OK
OK
OK
Mefloquine
OK*
NO
NO
OK
NO
NO
Doxycycline
NO
NO
OK
OK
OK
OK
Malarone
NO
NO
OK
OK
OK
OK
*
These drugs are not suitable during
the first trimester of pregnancy.
Childrens'
Dosages: Calculate
the dose by weight rather than by
age if possible
Age/Weight
Chloroquine
(once weekly)
Proguanil
(once daily)
Mefloquine
(once weekly)
Doxycycline
(once daily)
Malarone
(once daily)
0
- 12 weeks
under 6kg
¼
tablet
¼
tablet
-
-
-
3
- 12 months
6 - 10kg
½
tablet
½
tablet
¼
tablet
-
-
1
- 3 years
10 - 16kg
¾
tablet
¾
tablet
¼
tablet
-
1
child's
tablet
4
- 7 years
16 - 25kg
1
tablet
1
tablet
½
tablet
-
1
child's
tablet
8
- 12 years
25 - 45 Kg
1½
tablets
1½
tablets
¾
tablet
-
2
child's
tablets
13
years and over
45kg and over
2
tablets
2
tablets
1
tablet
1
capsule
1
adult
tablet
The
above dosages are based upon the guidelines
issued by
the Advisory Committee on Malaria
Prevention.
Adult
Dosages
Regimen
Dose
for
Chemoprophylaxis
Usual
amount
per tablet (mg)
Areas
without drug resistance:
Chloroquine
Proguanil
2
tablets weekly
2
tablets daily
150mg
(base)
100mg
Areas
of little chloroquine resistance (poorly
effective where marked resistance):